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Researchers discover drug that could combat brain cell death in those with Alzheimer’s disease.

Dr. Lin Jiang, Assistant Professor of Neurology at David Geffen School of Medicine at UCLA, was featured in an October 22 UCLA Newsroom article about him and his team members identified the plaque binding site of b-amyloid to its receptor by determining the three-dimensional structure. Knowledge of this interaction is a critical first step toward finding a drug to prevent the interaction between the toxic proteins and brain cells. Dr. Jiang and his team are using computer software to assist them in the drug selection process.

Alzheimer's Association® - AAIC 2018 News Highlights

The Alzheimer’s Association® - is committed to advocating awareness of latest Alzheimer’s research and resources. Each year, the organization brings together the world’s renowned basic science and clinical researchers, early career investigators, clinicians and the care research community to share advancements in dementia science and explore the latest information on products and services. Please visit the Alzheimer’s Association® website for the Alzheimer’s Association International Conference (AAIC) 2018 news highlights.

Molecule halts spread of toxic protein associated with Alzheimer’s.

UCLA Newsroom, EurekAlert, Science Magazine, Science Daily, Drug Discovery and Development, Health Canal, Medical Express, Scicasts and Medicine News Line reported on research showing a promising new drug strategy to halt tau transmission to treat Alzheimer’s. Varghese John, an Associate Professor of Neurology at the David Geffen School of Medicine at UCLA, and Karen Gylys, a Professor at the School of Nursing, were quoted.

Disrupted sleep-wake cycle might be a measure for preclinical Alzheimer’s.

National Institute of Health – National Institute on Aging - Report - Disrupted sleep-wake cycle might be a measure for preclinical Alzheimer's - People with dementia due to Alzheimer’s disease are known to have disrupted sleep. New NIH-funded research, published online Jan. 29, 2018, in JAMA Neurology, links a disrupted sleep-wake cycle to an earlier, preclinical disease phase, in which people have evidence of the disease but no symptoms. The study, by researchers at the Knight Alzheimer's Disease Research Center at Washington University in St. Louis, Missouri, suggests that a fragmented sleep-wake cycle might be explored as a biomarker for preclinical Alzheimer's.

Leafy greens linked with slower age-related cognitive decline.

National Institute of Health – National Institute on Aging - Report - Leafy greens linked with slower age-related cognitive decline - A recent report in the journal Neurology found that a diet containing approximately one serving of green leafy vegetables per day is associated with slower age-related cognitive decline.