Apostolova, Liana G., M.D., M.S.C.R.
  • Associate Professor in Residence of Neurology, David Geffen School of Medicine at UCLA

  • Director of Neuroimaging laboratory, Mary S. Easton Center for Alzheimer's Disease Research at UCLA

  • Neuroimaging and Biomarkers Core Leader

  • Director of Donor Relations for the Alzheimer's Disease Program

Apostolova, Liana G., M.D., M.S.C.R.

Contact

Mary S. Easton Center for Alzheimer's Disease Research at UCLA
10911 Weyburn Avenue, Suite 200
Los Angeles, CA 90095-7226
Tel: (310) 794-3665
Fax: (310) 794-3148
Appointments: (310) 794-6039 {Memory Evaluation}
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Specialty

Neurology, Alzheimer's Disease, Dementia, and Memory Disorders.

Top

Current Research

Dr. Apostolova conducts clinical and neuroimaging research in Alzheimer's disease, mild cognitive impairment and other neurodegenerative disorders. Her main research focus is the development and validation structural imaging biomarkers in Alzheimer’s disease and mild cognitive impairment both from an epidemiological and pharmacotherapeutic perspective. This important research dimension is in line with the increased interest in disease-associated biomarkers that will allow us to diagnose and treat dementia as early as possible. In addition she studies the brain-behavior correlations in Alzheimer’s disease, Parkinson’s disease and other dementias.

Top

Education

  • M.D., Medicine, Medical University, Sofia, Bulgaria, 1998.
  • Internship, Medicine, Ravenswood Hospital, Chicago, IL, 2000.
  • Residency, Neurology, University of Iowa Hospitals and Clinics, Iowa City, IA, 2003.
  • Fellowship, Dementia/Behavioral Neurology, University of California, Los Angeles, 2005.
  • Masters Sci Clin Res, Clinical Research Methodology, University of California, Los Angeles, 2010.

Top

Honors and Awards

1998 Summa-cum-laude, Medical University, Sofia, Bulgaria.
1992-1998 Full Tuition National Scholarship.
1992-1998 National Merit Scholarship.
1993-1998 Chilov Annual Scholarship.
2003 Physician Recognition Award, American Academy of Neurology.
2003-2005 Tichi Wilkerson-Kassel Dementia Fellow and Clinical Instructor, UCLA, California.
2005-2010 NIA K23 Paul Beeson Career Development Award in Aging.
2007 Turken Award and Endowment Recipient.
2009 Travel Award, 12th International Conference on Alzheimer’s Disease, Vienna, Austria.
2009 Seed Grant Award Recipient.
2010 Guest editor, Alzheimer's Disease and MCI: Benefits of Early Diagnosis and Treatment, CME-Newsletter.
2010 NINDS Advisory panel member - Biomarkers for Lewy Body Disease: Pathway to Discovery and Validation.
2010 American Academy of Neurology Research Award in Geriatric Neurology.
2010 AFAR-GE Healthcare Junior Investigator Award for Excellence in Imaging and Aging Research.
2010 Best Mentor Award, Medical Students Training in Aging Research Program.
2011-present Hippocampal Harmonization Protocol - Delphi Panelist and Master Tracer.
2011 David Geffen School of Medicine at UCLA Finalist for the AAMC Mid-Career Women Faculty Professional Seminar bestowed upon a single female School of Medicine faculty member each year.
2012 Selected as one of only three AD imaging experts for an Evidence-Based Medicine Expert Debate Webcast on the role of neuroimaging in the diagnosis of Alzheimer's disease.
2012 Invited as one of only four Imaging Expert Discussants of the major biomarker findings from the 2012 AAIC meeting for a MedScape webcast feature at the 2012 AAIC meeting in Vancouver, CA.
2012-2017 NIH NIA-N study section, permanent member.
2012 Member, UCLA Alzheimer's Program Director Search Committee.
2012-2013 Beeson Outreach Fund Travel Scholar, Indiana University ADRC and Imaging Genetics Laboratory.
2012 Eli Lilly Speakers Bureau - Amyvid™ Rater Trainer.
2012 Elected faculty, UCLA Interdepartmental Ph.D. Program for Neuroscience.
2013 Dorothy Dillon Eweson Lecturer on the Advances in Aging Research for 2013 AHA International Stroke Conference Presentation entitled "Molecular Neuroimaging in Dementia Research: Current Status."

Top

Professional Membership

  • American Academy of Neurology
  • American Academy of Neurology-Section of Geriatric Neurology
  • Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment
  • Organization of Human Brain Mapping
  • Brain Research Institute
  • Alzheimer’s Association Advocate Network

Top

Publications (selected peer-reviewed publications)

  • Apostolova LG, Dutton RA, Dinov ID, Toga AW, Cummings JL, Thompson PM. Conversion of mild cognitive impairment to Alzheimer disease predicted by hippocampal atrophy maps. Archives of Neurology 2006;63:693-699. PMID: 16682538
  • Apostolova LG, Dinov ID, Dutton RA, Hayashi KH, Toga AW, Cummings JL, Thompson PM. 3D comparison of hippocampal atrophy in amnestic mild cognitive impairment and Alzheimer's disease. Brain 2006;129:2867-2873; published online October 3, 2006; http://dx.doi.org/10.1093/brain/awl274. PMID: 17018552
  • Apostolova LG, Steiner CA, Akopyan GG, Dutton RA, Hayashi KM, Toga AW, Cummings JL, Thompson PM. 3D gray matter atrophy mapping in mild cognitive impairment and mild Alzheimer's disease. Arch Neurol 2007;64(10):1489-1495. PMID: 17923632
  • Ringman J, O'Neill J, Geschwind D, Medina L, Apostolova LG, Rodriguez Y, Medina L, Rodriguez Y, Schaffer B, Varpetian A, Tseng B, Ortiz F, Fitten J, Cummings JL, Bartzokis G. Diffusion tensor imaging in preclinical and presymptomatic carriers of familial Alzheimer's disease mutations. Brain 2007;130:1767-1776; published online May 23, 2007; http://dx.doi.org/10.1093/brain/awm102.
  • Apostolova LG, Akopyan GG, Partiali N, Steiner CA, Dutton RA, Hayashi KM, Dinov ID, Toga AW, Cummings JL, Thompson PM. Structural correlates of apathy in Alzheimer's disease. Dementia and Geriatric Cognitive Disorders 2007;24:91-97; published online June 6, 2007; http://dx.doi.org/10.1059/000103914.
  • Apostolova LG, Lu PH, Rogers SA, Dutton RA, Hayashi KM, Toga AW, Cummings JL, Thompson PM. 3D mapping of language networks in clinical and pre-clinical Alzheimer's disease. Brain and Language 2008;104(1):33-41; published online May 7, 2007; http://dx.doi.org/10.1016/j.bandl.2007.03.008. PMCID: PMC2211373
  • Morra JH, Tu Z, Apostolova LG, Green AE, Avedissian C, Madsen SK, Parikshak N, Hua X, Toga AW, Jack CR, Schuff N, Weiner MW, Thompson PM. Mapping hippocampal degeneration in 400 subjects with a novel automated segmentation approach. 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2008. ISBI, Paris 2008:336-339; http://dx.doi.org/10.1109/ISBI.2008.4541001.
  • Apostolova LG, Cummings JL. Neuropsychiatric manifestations in mild cognitive impairment: a systematic review of the literature. Dementia Geriatr Cog Disord 2008;25(2):115-126; published online Dec 14 2007; http://dx.doi.org/10.1159/000112509. PMID: 18087152
  • Morra JH, Tu Z, Apostolova LG, Green AE, Toga AW, Thompson PM. Automatic Subcortical Segmentation Using a Contextual Model. Med Image Comput Comput Assist Interv Int Conf 2008;11(Pt 1);194-201.
  • Morra JH, Tu Z, Apostolova LG, Green AE, Avedissian C, Madsen SK, Parikshak N, Hua X, Toga AW, Jack CR, Schuff N, Weiner MW, Thompson PM and the ADNI. Validation of a fully automated 3D hippocampal segmentation method using subjects with Alzheimer's disease, mild cognitive impairment and elderly controls. NeuroImage 2008;43(1):59-68. http://dx.doi.org/10.1016/j.neuroimage.2008.07.003. PMID: 18675918; PMCID: PMC2624575
  • Morra JH, Tu Z, Apostolova LG, Green AE, Avedissian C, Madsen SK, Parikshak N, Toga AW, Jack CR, Schuff N, Weiner MW, Thompson PM. Automated mapping of hippocampal atrophy in 1-year Repeat MRI Data in 490 subjects with Alzheimer's disease, mild cognitive imparment and elderly controls. Neuroimage, Special Issue on Mathematics in Brain Imaging 2009;45(1 Suppl):S3-S15. PMID: 19041724; PMCID: PMC2733354
  • Apostolova LG, Mosconi L, Thompson PM, Green AE, Hwang KS, Mistur R, Tsui WH, de Leon MJ. Subregional hippocampal atrophy predicts future decline to Alzheimer's dementia in cognitively normal subjects. Neurobiology of Aging 2010;31(7):1077-1088; epub in 2009: http://dx.doi.org/10.1016/j.neurobiolaging.2008.08.008. PMID: 18814937; PMCID: PMC2873083
  • Morra JH, Tu Z, Apostolova LG, Green AE, Madsen SK, Parikshak N, Hua X, Toga AW, Jack CR, Schuff N, Weiner MW, Thompson PM. Automated 3D mapping of hippocampal atrophy and its clinical correlates in 400 subjects with Alzheimer's disease, mild cognitive impairment and elderly controls. Human Brain Mapping 2009;30(9):2766-2788. PMID: 19172649; PMC2733926
  • Morra JH, Tu Z, Apostolova LG, Green AE, Madsen SK, Parikshak N, Toga AW, Jack CR, Weiner MW, Thompson PM. Automated mapping of hippocampal atrophy in 1-year repeat MRI data from 490 subjects with Alzheimer's disease, mild cognitive impairment and elderly controls. Neuroimage 2009;45(1 Suppl):S3-S15; http://dx.doi.org/10.1016/j.neuroimage.2008.10.043. PMID: 19041724; PMCID: PMC2733354
  • Apostolova LG, Thompson PM, Rogers SA, Dinov ID, Zoumalan C, Steiner CA, Siu E, Green AE, Small GW, Toga AW, Cummings JL, Phelps ME, Silverman DHS. Surface feature-guided mapping of cerebral metabolic changes in cognitively normal and mildly impaired elderly. Molecular Imaging and Biology 2010;12(2):218-224; http://dx.doi.org/10.1007/s11307-009-0247-7. PMID: 19636640; PMCID: PMC2844536
  • Morra JH, Tu Z, Apostolova LG, Green AE, Toga AW, Thompson PM. Comparison of AdaBoost and Support Vector Machines for detecting Alzheimer's disease through automated hippocampal segmentation. IEEE Transactions on Medical Imaging 2010;29(1):30-43. PMID: 19457748; PMCID: PMC2805054
  • Apostolova LG, Thompson PM, Green, AE, Hwang KS, Zoumalan C, Jack, CR, Harvey D, Petersen RC, Thal LJ, Aisen RS, Toga AW, Cummings JL, DeCarli C. 3D comparison of low, intermediate and advanced hippocampal atrophy in MCI. HBM 2010;31(5):786-797. PMID: 20143386; PMCID: PMC2938765
  • Apostolova LG, Beyer MK, Green AE, Hwang KS, Morra JH, Chou Y, Avedissian C, Aarsland D, Janvin CC, Larsen JP, Cummings JL, Thompson PM. Hippocampal, caudate, and ventricular changes in Parkinson’s disease with and without dementia. Mov Dis 2010; 25(6):687-688; doi: 10.1002/mds.22799.. PMID: 20437538; PMCID: PMC3068920
  • Apostolova LG, Morra JH, Green AE, Hwang K, Avedissian C, Woo E, Cummings JL, Toga AW, Jack CR, Weiner MW, Thompson PM. Automated 3D mapping of baseline and 12-month associations between three verbal memory measures and hippocampal atrophy in 490 ADNI subjects. Neuroimage 2010;51(1): 488-499; http://dx.doi.org/10.1016/j.neuroimage.2009.12.125. PMID: 20083211; PMCID: PMC2847034
  • Apostolova LG,(guest editor). Alzheimer's Disease and MCI: Benefits of Early Diagnosis and Treatment. A CME-Newsletter. www.adcme.com
  • Apostolova LG, Hwang KS, Andrawis JP, Green AE, Babakchanian S, Morra JH, Cummings JL, Toga AW, Trojanowski JQ, Shaw LM, Jack CRJ, Koeppe RA, Mathis CA, Weiner MW, Thompson PM. 3D PIB and CSF biomarker associations with hippocampal atrophy in ADNI subjects. Neurobiol Aging, ADNI special issue 2010;31:1284-1303; epub http://dx.doi.org/10.1016/j.neurobiolaging.2010.05.003. PMID: 20538372; PMCID:PMC3051831
  • Andrawis J, Hwang KS, Green AE, Kotlerman J, Elashoff D, Morra JH, Cummings JL, Toga AW, Thompson PM, Apostolova LG. Effects of ApoE4 and maternal history of Alzheimer's disease on hippocampal atrophy. Neurobiol Aging, in press.; e-pub http://dx.doi.org/10.1016/j.neurobiolaging.2010.07.020. PMID: 20833446; PMCID: PMC3010297
  • Wolk DA, Dickerson BC, Alzheimer's Disease Neuroimaging Initiative, Weiner M, Aiello M, Aisen P, Albert MS, Alexander G, Anderson HS, Anderson K, Apostolova L, Arnold S, Ashford W, Assaly M, Asthana S, Bandy D, Bartha R, Bates V, Beckett L, Bell KL, Benincasa AL, Bergman H, Bernick C, Bernstein M, Black S. Apolipoprotein E (APOE) genotype has dissociable effects on memory and attentional-executive network function in Alzheimer's disease. Proc Natl Acad Sci U S A 2010 Jun 1;107(22):10256-10261. PMID: 20479234; PMCID: PMC2890481
  • Ringman JM, Medina L, Gylys KH, Fox M, Kepe V, Flores D, Barrio J, Small GW, Siu E, Cederbaum S, Bird T, Apostolova LG, Hecimovic S, Malnar M, Chakraverty S, Goate AM, Leverenz JB. Biochemical, neuropathological and neuroimaging characteristics of early-onset Alzheimer's disease due to a novel PSEN1 mutation. Neuroscience Letters 2011;487:287-292. PMID: 21094210; PMCID: PMC3034479
  • Apostolova LG, Hwang KS, Medina LD, Green AE, Braskie MN, Dutton RA, Lai J, Geschwind DH, Cummings JL, Thompson PM, Ringman JM. Cortical and hippocampal atrophy in patients with autosomal dominant familial Alzheimer's disease. Dementia and Geriatric Cognitive Disorders2011;32:118-125. PMID: 21952501; PMCID: PMC3222115
  • Apostolova LG, Alves G, Hwang KS, Babakchanian S, Bronnick K, Larsen JP, Thompson PM, Chou Y, Tysnes OB, Beyer M. Hippocampal and ventricular changes in Parkinson's disease subjects with mild cognitive impairment. Neurobiol Aging 2011 Aug 1. [Epub ahead of print] PMID: 21813212
  • Apostolova LG, Green AE, Babakchanian S, Hwang KS, Chou Y, Cummings JL, Toga AW, Thompson PM. Hippocampal atrophy and ventricular enlargement in normal aging, mild cognitive impairment and Alzheimer's disease, ADAS, 2012;26(1):17-27. PMCID: PMC3286134
  • Chow N, Aarsland D, Honarpisheh H, Beyer MK, Rongve A, Tsynes OB, Thompson PM, Apostolova LG. Comparing hippocampal atrophy in Alzheimer'ls dementia and Dementia with Lewy Bodies. Dem Geriatr Cog Dis 2012;34(1):44-50. PMID: 22922563; PMCID: PMC3470878 [Available on 2013/8/20]
  • Stein JL, … Apostolova LG, …et al (ENIGMA consortium). Identification of common variants associated with human hippocampal and intracranial volumes. Nature Genetics 2012;44(5):552-561. PMID: 22504417; PMCID: PMC3635491
  • Prado E, Paholpak P, Ngo M, Porter V, Apostolova LG, Ringman JM. Agitation and psychosis associated with dementia with Lewy bodies exacerbated by Modafinil use. Amer J Alzheimer Dis Other Dem 2012;27(7):468-473. PMID: 22892657
  • Lee GJ, Lu PH, Medina L, Rodrigues Y, Melchor S, Coppola G, Braskie MN, Apostolova LG, Leow A, Thompson PM, Ringman JM. Regional brain volume differences in symptomatic and presymptomatic carriers of familial Alzheimer's disease mutations. J Neurol Neurosurg Psychiatry 2013;84(2):154-162. doi: 10.1136/jnnp-2011-302087. PMID: 23085935
  • Ringman JM, Bardens J, Teng E, Beigi M, Gylys K, Badmaev V, Heath DD, Frautchy S, Apostolova LG, Porter V, Vanek Z, Helleman G, Sugar C, Montine TJ, Cummings JL, Cole G. Oral curcumin for Alzheimer’s disease: Tolerability and efficacy in a 24-week randomized double blind placebo-controlled study. Alzheimers Res Ther 2012;4(5):43. PMID: 23107780
  • Grill JD, Di L, Lu PH, Lee C, Ringman J, Apostolova LG, Chow N, Kohannim O, Cummings JL, Thompson PM, Elashoff D, for the Alzheimer's Disease Neuroimaging Initiative. Estimating sample sizes for pre-dementia Alzheimer’s trials based on the Alzheimer’s Disease Neuroimaging Initiative. Neurobiol Aging 2013 34(1):62-72. PMID: 22503160; PMCID: PMC3412892 [Available on 2014/1/1]
  • Beyer MK, Bronninck KS, Hwang KS, Bergsland N, Tysnes OB, Larsen JP, Thompson PM, Somme JH, Apostolova LG. Verbal memory performance is associated with structural hippocampal changes in newly diagnosed Parkinson's disease. JNNP 2013;84(1):23-28.doi: 10.1136/jnnp-2012-303054. PMID: 23154124
  • Apostolova LG, Babakchanian S, Hwang KS, Green AE, Zlatev D, Chou YY, Jack CR, Petersen RC, Aisen PS, Cummings JL, Toga AW, Thompson PM. Ventricular atrophy and its clinical correlates in the imaging cohort from the ADCS MCI Donepezil/Vitamin E study. ADAD 2013;27(2):174-181. doi: 10.1097/WAD.0b013e3182677b3d; PMID: 23694947; PMCID: PMC3662002
  • Beyer M, Alves G, Hwang KS, Babakchanian S, Bronnick K, Chou Y, Dalaker TO, Kurz MW, Larsen JP, Somme JH, Thompson PM, Tysnes OB, Apostolova LG. Cerebrospinal fluid Aβ levels correlate with structural brainchanges in Parkinson’s disease. Mov Dis 2013;28(3):302-310. Doi:10.1002/mds.25282. PMID: 23408705; PMCID: PMC3608817
  • Hwang KH, Beyer MK, Green AE, Thompson PM, Janvin C, Larsen JP, Cummings JL, Aarsland D, Apostolova LG. Mapping cortical atrophy in Parkinson’s disease patients with cognitive impairment and dementia. Dementia and Geriatric Cognitive Disorders 2013;3(1):69-76. doi: 10.3233/JPD-120151. PMID: 23938313
  • Teng E, Leone-Friedman J, Lee GJ, Woo S, Apostolova LG, Harrell S, Ringman JM, Lu PH. Siimilar verbal fluency patterns in amnestic mild cognitive impairment and Alzheimer’s disease. Arch Clin Neuropsychol 2013:28(5):400-410. doi: 10.1093/arclin/act039. PMID: 23752677; PMCID: PMC3711375
  • Kilroy E, Apostolova LG, Liu CY, Yan L, Ringman J, Wang DJ. Reliability of 2D and 3D pseudo-continuous arterial spin labeling perfusion MRI in elderly populations – comparison with 15O-water PET J Magn Reson Imaging, 2013 September 13. doi: 10.1002/jmri.24246. PMID: 24038544
  • Kohannim O, Hua X, Rajagopalan P, Hibar DP, Jahanshad N, Grill J, Apostolova LG, Toga AW, Jack CR, Weiner MW, Thompson PM. Multilocus genetic profiling to empower drug trials and predict brain atrophy. Neuroimage Clinical, 2013 in press.
  • Apostolova LG, Di LJ, Elashoff D, Tseng CH, Fairbanks L, Cummings JL. Risk factors for behavioral abnormalities in mild cognitive impairment and mild Alzheimer’s disease. Dem Geriatr Cog Dis, 2013 in press.

Book Chapters

  • Apostolova LG, Cummings JL. Neuropsychiatric Features of Dementia with Lewy Bodies. Chapter in Dementia with Lewy Bodies, O'Brien J, McKeith I, Ames D, Chui E (eds), 2006, Taylor and Francis Group: Oxon, UK, p. 73-92.
  • Apostolova LG, Cummings JL. The pathogenesis of m Alzheimer's disease. Chapter for Protein Misfolding, Aggregation, and Conformational Diseases, vol. II. Uversky, Fink AL (eds), 2007, Springer Science+Business Media: New York, NY, p. 3-29.
  • Apostolova LG, Cummings JL. Neuropsychiatric aspects of Alzheimer's Disease and other dementing illnesses. Chapter for The American Psychiatric Pubishing textbook of Neuropsychiatry, 5th Edition. Yudofsky SC, Hales RE (eds), 2007, American Psychiatric Publishing, Inc.: Washington, DC, p. 935-968.
  • Apostolova LG, Thompson PM. Imaging of cognitive disorders. Chapter for Imaging of Neuropsychiatric Disorders, 1st Edition. Turetsky B, Shenton M (eds), 2011, Cambridge University Press, New York, NY, p 313-331.
  • Leow AD, Apostolova LG, Thompson PM. Computation Anatomy in Alzheimer's Disease. Chapter for Principles and Practice of Geriatric Psychiatry, 3rd edition. Abou-Saleh M, Katona C, Kumar A (eds), 2011, John Wiley and Sons, Ltd., Chichester, England, p. 262-270.
  • Apostolova LG, DeKoski S, Cummings JL. Dementia. Chapter for Neurology in Clinical Practice, 6th edition. Daroff R, Fenichel G, Jankovic J, Mazziotta J (eds), 2012, Elsevier: Phladelphia, PA, p. 1534-1582.
  • Apostolova LG, Cummings JL. Neuropsychiatric aspects of Alzheimer's Disease and other dementing illnesses. Chapter for The Manual of Clinical Neuropsychiatry,1st edition. Yudofsky SC, Hales RE (eds), 2012, American Psychiatric Publishing, Inc.: Washington, DC, p.311-338.
  • Apostolova LG. Structural Imaging in Degenerative Dementias. Chapter for Textbook for Geriatric Neurology. Sabbagh M, Nair A (eds). Pearson/Prentice-Hall, in press.
  • Beyer M, Dalaker T, Apostolova LG. Imaging and Behavior in Pakrinson's disease. Chapter for Behavioral problems in Parkinson's disease: Diagnosis and Management. Aarsland D, Cummings JL, Weintraub D, Chaudhuri R (eds). Cambridge University Press, in press.
  • Apostolova LG. Dementia. Chapter for Best Practices In Neurological Care, Ovbiagele B. (ed). Future Science Group, London, in press.

Abstracts

  • Boccardi M, Bocchetta M, Apostolova LG, Barnes J, et al. Delphi consensus for a harmonized protocol for manual hippocampal segmentation: an EADC-ADNI Project. 15th Alzheimer Association International Conference, Vancouver, Canada, July 2012; oral presentation.
  • Hwang KH, Coppola G, Klein E, Thompson PM, Cummings JL, Apostolova LG. Microtubule-associated protein tau H2 haplotype is associated with frontotemporal atrophy in cognitively normal elderly. 15th Alzheimer Association International Conference, Vancouver, Canada, July 2012; oral presentation.
  • Woo E, Ben-Ami J, Lin B, Obermeit L, Romero E, Amaya S, Siders CA, Lu PH, Ringman J, Apostolova LG, Wright MJ. Encoding deficits in mild cognitive impairment predict activities of daily living. 15th Alzheimer Association International Conference, Vancouver, Canada, July 2012.
  • Boccardi M, Bocchetta M, Apostolova LG, Barnes J, Bartzokis G, Corbetta G, deCarli C, deToledo-Morrell L, Firbank M, Ganzola R, Gerritsen L, Henneman W, Killiany RJ, Malykhin N, Pasqualetti P, Pruessner JC,Redolfi A, Robitaille N, Soininen H, Tolomeo D, WangL, Watson C, Wolf H, Duchesne S, Jack CR Jr, Frisoni GB. Definition of Harmonized Protocol for Hippocampal Segmentation. 5th Clinical Trails Conference on Alzhiemer’s Disease, Monte Carlo, October 29-31, 2012.
  • Boccardi M, Bocchetta M, Corbetta G, et al. (Apostolova LG as part of the Harmonized Protocol group). Definition of harmonized protocol for hippocampal segmentation. 2012 DGPPN congress, Berlin, Germany, November 2012; oral presentation.
  • Eastman JA, Hwang KH, Lazaris A, Chow N, Ramirez L, Babakchanian S, Woo E, Apostolova LG. 3D Mapping of Verbal Fluency in Alzheimer’s Disease. 2013 International Neuropsychological Society Meeting, Waikaloa, Hawaii, February 6-9, 2013.
  • Ben-Ami J,Izaguirre B, McLaughlin P, Lin B, Maurer M, Apostolova LG, Ringman JM, Tingus KD, Wright MJ, Woo E. The Roles of Semantic and Serial Clustering in Everyday Functioning in Mild Cognitive Impairment. 2013 International Neuropsychological Society Meeting, Waikaloa, Hawaii, February 6-9, 2013.
  • Izaguirre B, Ben-Ami J, McLaughlin P, Rajagopal M, He A, Apostolova LG, Ringman JM, Tingus KD, Woo E. The Cognitive Foundations of Memory Strategy Use in Mild Cognitive Impairment. 2013 International Neuropsychological Society Meeting, Waikaloa, Hawaii, February 6-9, 2013.
  • Boccardi M, Bocchetta M, Apostolova LG, et al. Definition of Harmonized Protocol for Hippocampal Segmentation. 11th International Conference on Alzheimer's and Parkinson's Diseases, Florence, Italy, March 2013.
  • Apostolova LG, Hwang KH, Kohannim O, Jack CR, Shaw L, Trojanowski JQ, Weiner MW, Thompson PM. Presence of brain amyloidosis can be ascertained from cognitive, imaging and peripheral blood protein measures. 65th American Academy of Neurology Meeting, San Diego, March 16-23, 2013. Oral Poster Presentation Tour: Alzheimer’s Biomarkers in Clinical Practice Integrated Neuroscience Session.
  • Babakchanian S, Chow N, Green AE, Somme JH, Hwang KS, Jack CR, Thompson PM, Apostolova LG. Automated and Manual Hippocampal Segmentation Techniques: A Comparison of Results and Reproducibility. 65th American Academy of Neurology Meeting, San Diego, March 16-23, 2013.
  • Boccardi M, Bocchetta M, Apostolova LG, Ganzola R, Preboske G, Wolf D, Pasqualetti P, Robitaille N, Duchesne S, Jack CR, Frisoni GB. EADC-ADNI Benchmark Images of Harmonized Hippocampal Segmentation. 65th American Academy of Neurology Meeting, San Diego, March 16-23, 2013.
  • Chow N, Hwang KS, Babakchanian S, Thompson PM, Jack CR, Weiner MW, Apostolova LG. Comparing 3T and 1.5T MRI for Mapping Hippocampal Atrophy in the Alzheimer's Disease Neuroimaging Initiative (ADNI). 65th American Academy of Neurology Meeting, San Diego, March 16-23, 2013.
  • Eastman JA, Hwang KH, Lazaris A, Chow N, Ramirez L, Babakchanian S, Woo E, Thompson PM, Apostolova LG. The Relationship Between Cortical Thickness and Semantic Fluency. 65th American Academy of Neurology Meeting, San Diego, March 16-23, 2013.
  • Hwang KH, Kohannim O, Jack CR, Shaw L, Trojanowski JQ, Weiner MW, Thompson PM, Apostolova LG. Automated diagnostic classifiers for mild cognitive impairment and Alzheimer's disease. 65th American Academy of Neurology Meeting, San Diego, March 16-23, 2013.
  • Ramirez L, Hwang KH, Eastman JA, Babakchanian S, Sears R, Klein E, Gao F, Coppola G. Thompson PM, Apostolova LG. Common variants in ABCA7, MS4A6, and PICALM are associated with cortical atrophy. 65th American Academy of Neurology Meeting, San Diego, March 16-23, 2013.
  • Ringman JM, Sears R, Gao F, Lane L, Hsu SC, Klein E, Wharton D, B.A., Hwang K, Apostolova LG, Coppola G. Decreased expression of peptidase inhibitors in peripheral blood from familial Alzheimer's disease mutation carriers. 65th American Academy of Neurology Meeting, San Diego, March 16-23, 2013; oral presentation.
  • Jiang D, Hwang KS, Bordelon Y, Apostolova LG. Cortical Atrophy and Gene Expression in Parkinson's Disease with Mild Cognitive Impairmen. American Geriatrics Society meeting, Grapevine, TX, May 2013.
  • Scott T, Avila J, Woo E, Apostolova LG, Ringman J, Lu P, Razani J. Classifying Individuals with MCI and Healthy Elderly With a Daily Activities Task. 25th Annual Convention of the Association for Psychological Science, Washington DC, May 23-26, 2013.
  • Chow N, Hwang KS, Babakchanian S, Thompson PM, Jack CR, Weiner MW, Apostolova LG. Mapping Hippocampal Atrophy in 3T and 1.5T MRI. 19th OHBM Meeting, Seattle, June 2013.
  • Boccardi M, Robitaille N, Valdivia F, Bocchetta M, Bauer C, Blair M, Burton E, Cavedo E, Christensen A, Frederiksen KS, Grothe MJ, Lanfredi M, Liu Y, Martinez O, Nishikawa M, Portegies M, Pronk M, Stoub T, Swihart T, Ward C, Apostolova LG, Ganzola R, Preboske G, Wolf D, Jack CR, Duchesne S, Frisoni GB. Training for Manual Hippocampal Segmentation based on the EADC-ADNI Harmonized Protocol. 16th Alzheimer Association International Conference, Boston, MA, July 2013.
  • Duchesne S, Valdivia F, Robitaille N, Valdivia A, Apostolova LG, Bocchetta M, Ganzola R, Preboske G, Wolf D, Boccardi M, Jack CR Jr, Frisoni GB , for the EADC-ADNI Working Group on The Harmonized Protocol for Hippocampal Volumetry and for the Alzheimer’s Disease Neuroimaging Initiative. Manual segmentation certification platform for the EADC-ADNI Harmonized Protocol for Hippocampal Volumetry Project. 16th Alzheimer Association International Conference and Alzheimer Imaging Consortium, Boston, MA, July 2013.
  • Clark, DG, Hwang, K, McLaughlin, P, Babakchanian, S, Woo E, Apostolova, LG. Gray Matter Correlates of Alzheimer's Risk as Quantified With Latent Information in Semantic Fluency Lists. 16th Alzheimer Association International Conference and Alzheimer Imaging Consortium, Boston, MA, July 2013.
  • Babakchanian S, Somme J, Honarpisheh H, Hwang K, Biado K, Tung S, Frew A, Alger J, Wisco J, Schettler SP, Zarow C, Vinters HV, Apostolova LG. The Relationship between hippocampal atrophy and neuropathology markers: a 7T study. 16th Alzheimer Association International Conference and Alzheimer Imaging Consortium, Boston, MA, July 2013.
  • Apostolova LG, Hwang KS, Ramirez LM, Sears R, Klein E, Gao F, Horvath S, Thompson PM, Cummings JL, Coppola G. A gene co-expression module in peripheral blood correlates with hippocampal atrophy in elderly subjects. 16th Alzheimer Association International Conference and Alzheimer Imaging Consortium, Boston, MA, July 2013.
  • Hwang KS, Lazaris A, Eastman J, Teng E, Koeppe RA, Thompson PM, Gylys K, Cole G, Jack CR, Jr., Shaw L, Soares H, Trojanowski J, Weiner MW, Apostolova LG. Peripheral blood plasma protein levels associate with Pittsburgh compound B binding in the brain. 16th Alzheimer Association International Conference and Alzheimer Imaging Consortium, Boston, MA, July 2013.

Top